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Atypical gut microbial ecosystem from athletes with very high exercise capacity improves insulin sensitivity and muscle glycogen store in mice.
Martin D, Bonneau M, Orfila L, Horeau M, Hazon M, Demay R, Lecommandeur E, Boumpoutou R, Guillotel A, Guillemot P, Croyal M, Cressard P, Cressard C, Cuzol A, Monbet V, Derbré F.
Cell Rep. 2025 Mar 19:115448. doi: 10.1016/j.celrep.2025.115448. Online ahead of print.
PMID: 40154488
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Dry immersion rapidly disturbs iron metabolism in men and women: results from the VIVALDI studies.
Horeau M, Navasiolava N, Van Ombergen A, Custaud MA, Robin A, Ropert M, Antunes I, Bareille MP, Billette De Villemeur R, Gauquelin-Koch G, Derbré F, Loréal O.
NPJ Microgravity. 2024 Jun 15;10(1):68. doi: 10.1038/s41526-024-00399-z.
PMID: 38879550 Free PMC article.
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4.
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The Yucatan minipig model: A new preclinical model of malnutrition in obese patients with acute or chronic diseases.
Couvert A, Lacaze L, Touboulic S, Gautier S, Guérin S, Randuineau G, Romé V, Malbert CH, Val-Laillet D, Derbré F, Thibault R.
Clin Nutr. 2024 Feb;43(2):357-365. doi: 10.1016/j.clnu.2023.12.003. Epub 2023 Dec 15.
PMID: 38142480
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Differences in bone microarchitecture between genetic and secondary iron-overload mouse models suggest a role for hepcidin deficiency in iron-related osteoporosis.
Robin F, Chappard D, Leroyer P, Latour C, Mabilleau G, Monbet V, Cavey T, Horeau M, Derbré F, Roth MP, Ropert M, Guggenbuhl P, Loréal O.
FASEB J. 2023 Nov;37(11):e23245. doi: 10.1096/fj.202301184R.
PMID: 37874260
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6.
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The Yucatan minipig model: A new preclinical model of malnutrition induced by a low-calorie/low-protein diet.
Lacaze L, Rochdi S, Couvert A, Touboulic S, Guérin S, Randuineau G, Martin D, Romé V, Malbert CH, Derbré F, Val-Laillet D, Thibault R.
Clin Nutr. 2022 Oct;41(10):2077-2086. doi: 10.1016/j.clnu.2022.08.002. Epub 2022 Aug 10.
PMID: 36063575
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8.
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9.
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Oxidative and glycolytic skeletal muscles deploy protective mechanisms to avoid atrophy under pathophysiological iron overload.
Martin D, Nay K, Robin F, Rebillard A, Orfila L, Martin B, Leroyer P, Guggenbuhl P, Dufresne S, Noirez P, Ropert M, Loréal O, Derbré F.
J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1250-1261. doi: 10.1002/jcsm.12897. Epub 2022 Feb 3.
PMID: 35118832 Free PMC article.
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10.
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Does Physical Inactivity Induce Significant Changes in Human Gut Microbiota? New Answers Using the Dry Immersion Hypoactivity Model.
Jollet M, Nay K, Chopard A, Bareille MP, Beck A, Ollendorff V, Vernus B, Bonnieu A, Mariadassou M, Rué O, Derbré F, Goustard B, Koechlin-Ramonatxo C.
Nutrients. 2021 Oct 29;13(11):3865. doi: 10.3390/nu13113865.
PMID: 34836120 Free PMC article. Clinical Trial.
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11.
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Simulated microgravity disturbs iron metabolism and distribution in humans: Lessons from dry immersion, an innovative ground-based human model.
Nay K, Koechlin-Ramonatxo C, Rochdi S, Island ML, Orfila L, Treffel L, Bareille MP, Beck A, Gauquelin-Koch G, Ropert M, Loréal O, Derbré F.
FASEB J. 2020 Nov;34(11):14920-14929. doi: 10.1096/fj.202001199RR. Epub 2020 Sep 12.
PMID: 32918768 Clinical Trial.
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12.
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Intermittent reloading does not prevent reduction in iron availability and hepcidin upregulation caused by hindlimb unloading.
Nay K, Martin D, Orfila L, Saligaut D, Martin B, Horeau M, Cavey T, Kenawi M, Island ML, Ropert M, Loréal O, Koechlin-Ramonatxo C, Derbré F.
Exp Physiol. 2021 Jan;106(1):28-36. doi: 10.1113/EP088339. Epub 2020 May 19.
PMID: 32281155
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13.
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Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia.
Kenawi M, Rouger E, Island ML, Leroyer P, Robin F, Rémy S, Tesson L, Anegon I, Nay K, Derbré F, Brissot P, Ropert M, Cavey T, Loréal O.
FASEB J. 2019 Dec;33(12):13492-13502. doi: 10.1096/fj.201901106R. Epub 2019 Sep 27.
PMID: 31560858
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Gut bacteria are critical for optimal muscle function: a potential link with glucose homeostasis.
Nay K, Jollet M, Goustard B, Baati N, Vernus B, Pontones M, Lefeuvre-Orfila L, Bendavid C, Rué O, Mariadassou M, Bonnieu A, Ollendorff V, Lepage P, Derbré F, Koechlin-Ramonatxo C.
Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E158-E171. doi: 10.1152/ajpendo.00521.2018. Epub 2019 Apr 30.
PMID: 31039010
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15.
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Skeletal muscle ceramides do not contribute to physical-inactivity-induced insulin resistance.
Appriou Z, Nay K, Pierre N, Saligaut D, Lefeuvre-Orfila L, Martin B, Cavey T, Ropert M, Loréal O, Rannou-Bekono F, Derbré F.
Appl Physiol Nutr Metab. 2019 Nov;44(11):1180-1188. doi: 10.1139/apnm-2018-0850. Epub 2019 Mar 19.
PMID: 30889368
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Allopurinol partially prevents disuse muscle atrophy in mice and humans.
Ferrando B, Gomez-Cabrera MC, Salvador-Pascual A, Puchades C, Derbré F, Gratas-Delamarche A, Laparre L, Olaso-Gonzalez G, Cerda M, Viosca E, Alabajos A, Sebastiá V, Alberich-Bayarri A, García-Castro F, Viña J.
Sci Rep. 2018 Feb 23;8(1):3549. doi: 10.1038/s41598-018-21552-1.
PMID: 29476130 Free PMC article.
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The Oxygen Paradox, the French Paradox, and age-related diseases.
Davies JMS, Cillard J, Friguet B, Cadenas E, Cadet J, Cayce R, Fishmann A, Liao D, Bulteau AL, Derbré F, Rébillard A, Burstein S, Hirsch E, Kloner RA, Jakowec M, Petzinger G, Sauce D, Sennlaub F, Limon I, Ursini F, Maiorino M, Economides C, Pike CJ, Cohen P, Salvayre AN, Halliday MR, Lundquist AJ, Jakowec NA, Mechta-Grigoriou F, Mericskay M, Mariani J, Li Z, Huang D, Grant E, Forman HJ, Finch CE, Sun PY, Pomatto LCD, Agbulut O, Warburton D, Neri C, Rouis M, Cillard P, Capeau J, Rosenbaum J, Davies KJA.
Geroscience. 2017 Dec;39(5-6):499-550. doi: 10.1007/s11357-017-0002-y. Epub 2017 Dec 21.
PMID: 29270905 Free PMC article. Review.
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