M2S Laboratory
Profile picture for user groussard_c@univ-rennes2.fr

Carole
Groussard

Enseignante - Chercheuse (PU) / Directrice adjointe de l'UFR STAPS en charge de la formation et de la pédagogie
Email
carole.groussard [at] univ-rennes2.fr
Université Rennes 2
Research axis
Practise

Carole Groussard
Univ-Rennes / M2S laboratory
Avenue Charles Tillon
UFR STAPS - CS 24414
35044 Rennes Cedex

My research focuses on the interactions between physical activity, nutrition and health, and more specifically on the effects of exercise and/or training, whether or not combined with biologically active ingredients, on pro/antioxidant status in humans and healthy or pathological animals.

I teach exercise physiology at various levels: from L1 to Master 2. My teaching focuses mainly on physiological adaptations to exercise and training (cardiovascular, respiratory, hormonal, muscular, etc.) in healthy subjects or specific populations (women, children, the elderly, pathological individuals). My Master's lectures focus on my research into oxidative stress and physical exercise.

CURRENT POSITIONS
University professor and associate director in charge of teaching and pedagogy at the Rennes 2 UFRSTAPS since 2014.
Lecturer and researcher at Rennes 2 University (UFR-STAPS) since 2002. 
Member of the EA 7470 research team, Movement, Sport, Health Laboratory (M2S) since 1995. 
Recipient of the Scientific Excellence Award (PES) / C3: 2012-2016 then 2016-2020 then 2020-2024.

HONOURS 
2023: Promoted to the rank of Officer of the Ordre des Palmes Académiques - July 2023.
2017: Promoted to the rank of ‘chevalier’ of the Ordre des palmes académiques - Promotion of July 2017.

ARTICLES PUBLISHED IN INTERNATIONAL PEER-REVIEWED JOURNALS

  1. Chaouachi M, Vincent S & Groussard C*. A review of the health-promoting properties of Spirulina with a focus on athletes’ performance and recovery (2023). J Diet Suppl. 2023 May 4:1-32. doi: 10.1080/19390211.2023.2208663. PMID: 37143238
  2. Chaouachi M, Gautier S, Carnot Y, Guillemot P, Pincemail J, Moison Y, Collin T, Groussard C* & Vincent S*[1] (2022). Spirulina supplementation prevents exercise-induced lipid peroxidation, inflammation and skeletal muscle damage in elite rugby players (2022). J Hum Nutr Diet. Dec;35(6):1151-1163. doi: 10.1111/jhn.13014.
  3. Groussard C, Plissonneau C, Josset L, Capel F, Mura M, Gouraud E, Mairesse G, Chesneau G, Barnich N, Pialoux V, Boisseau N. Beneficial Effects of High Intensity Interval Training and/or Linseed Oil Supplementation to Limit Obesity-Induced Oxidative Stress in High Fat Diet-Fed Rats (2021). Nutrients. Oct 9;13(10):3531. doi: 10.3390/nu13103531.PMID: 34684532
  4. Chaouachi M, Gautier S, Carnot Y, Bideau N, Guillemot P, Moison Y, Collin T, Vincent S*, Groussard C*[2]. Spirulina platensis Provides a Small Advantage in Vertical Jump and Sprint Performance But Does Not Improve Elite Rugby Players' Body Composition (2020). J Diet Suppl. 2021;18(6):682-697. doi: 10.1080/19390211.2020.1832639. Epub Oct 29.PMID: 33118429
  5. Groussard C, Maillard F, Vazeille E, Barnich N, Sirvent P, Otero YF, Combaret L, Madeuf E, Sourdrille A, Delcros G, Etienne M, Teixeira A, Sauvanet P, Pialoux V, Boisseau N. Tissue-Specific Oxidative Stress Modulation by Exercise: A Comparison between MICT and HIIT in an Obese Rat Model (2019). Oxid Med Cell Longev. Jul 14;2019:1965364.
  6. Youssef H, Zind M, Garnier S, Fazah A, Jacob C, Moussa E, Gratas-Delamarche A, Groussard C. Overweight and Obesity Related Factors among Lebanese Adolescents: An Explanation for Gender and Socioeconomic Differences (2017). Epidemiology (Sunnyvale), 7:2.
  7. Le Moal E, Pialoux V, Juban G, Groussard C, Zouhal H, Chazaud B, Mounier R. Redox control of skeletal muscle regeneration. Antioxid redox signal (2017). Aug 10;27(5):276-310.
  8. Le Moal E, Groussard C, Chaory K, Plantet K, Le Bris R, Pincemail J, Zouhal H. Redox status of professional soccer players is influenced by training load throughout a season(2016). Int J Sports Med. Aug;37(9):680-6.
  9. Groussard C, Rouchon-Isnard M, Coutard C, Romain F, Malardé L, Lemoine-Morel S, Martin B, Pereira B, Boisseau N. Beneficial effects of an intradialytic cycling training program in patients with end-stage kidney disease (2015). Appl Physiol Nutr Metab. Jun;40(6):550-6.
  10. Youssef H, Groussard C, Lemoine-Morel S, Pincemail J, Jacob C, Moussa E, Fazah A, Cillard J, Pineau JC, Delamarche A. Aerobic training suppresses exercise-induced lipid peroxidation and inflammation in overweight/obese adolescent girls (2015). Pediatr Exerc Sci. Feb;27(1):67-76.
  11. Malardé L, Groussard C, Lefeuvre-Orfila L, Vincent S, Efstathiou T, Gratas-Delamarche A. Fermented soy permeate reduces cytokine level and oxidative stress in streptozotocin-induced diabetic rats (2015). J Med Food. Jan;18(1):67-75.
  12. Owen AL, Wong DP, Dunlop G, Groussard C, Kebsi W, Dellal A, Morgans R, Zouhal H. High intensity training and salivary immunoglobulin-a responses in professional top-level soccer players: effect of training intensity (2014). J Strength Cond Res. Jan 19.
  13. Malardé L, Gratas-Delamarche A, Le Douairon-Lahaye S, Zguira MS, Vincent S, Lemoine-Morel S, Groussard C. Endurance training and insulin therapy need to be associated to fully exert their respective beneficial effects on oxidant stress and glycemic regulation in diabetic rats (2014). Free Radic Res. Apr;48(4):412-9
  14. Malardé L, Rebillard A, Le Douairon-Lahaye S, Vincent S, Zguira MS, Lemoine-Morel S, Gratas-Delamarche A, Groussard C. Superoxide production pathways in aortas of diabetic rats: beneficial effects of insulin therapy and endurance training (2014). Mol Cell Biochem. Apr;389(1-2):113-8.
  15. Malardé L, Vincent S, Lefeuvre-Orfila L, Efstathiou T, Groussard C**[3], Gratas-Delamarche A. A fermented soy permeate improves the skeletal muscle glucose level without restoring the glycogen content in streptozotocin-induced diabetic rats (2013). J Med Food. Feb;16(2):176-9.
  16. Zouhal H, Groussard C, Minter G, Vincent S, Cretual A, Gratas-Delamarche A, Delamarche P, Noakes TD. Inverse relationship between percentage body weight change and finishing time in 643 forty-two-kilometre marathon runners (2011). Br J Sports Med. 45(14):1101-5.
  17. Zouhal H, Jabbour G, Youssef H, Flaa A, Moussa E, Groussard C, Jacob C. Obesity and catecholamine responses to maximal exercise in adolescent girls (2010). Eur J Appl Physiol.110(2):247-54.
  18. El Hage R, Jacob C, Moussa E, Groussard C, Pineau JC, Benhamou CL, Jaffré C. Influence of the weight status on bone mineral content and bone mineral density in a group of Lebanese adolescent girls (2009). Joint Bone Spine.76(6):680-4,.
  19. Youssef H, Groussard C, Pincemail J, Moussa E, Jacob C, Lemoine S, Zind M, Defraigne JO, Cillard J, Delamarche P, Gratas-Delamarche A. Exercise-induced oxidative stress in overweight adolescent girls: roles of basal insulin resistance and inflammation and oxygen overconsumption (2009). Int J Obes (Lond). 33(4):447-55.
  20. Zouhal H, Groussard C, Vincent S, Jacob C, Abderrahman AB, Delamarche P, Gratas-Delamarche A. Athletic performance and weight changes during the "Marathon of Sands" in athletes well-trained in endurance (2009). Int J Sports Med. 30(7):516-21.
  21. El Hage R, Jacob C, Moussa E, Youssef H, Groussard C, Pineau JC, Jaffré C. [Leptin, insulin, IGF-1 and bone mass in a group of sedentary adolescent girls (2008).  J Med Liban. 56(4):220-5.
  22. Youssef H, Groussard C, Machefer G, Minella O, Couillard A, Knight J, Gratas-Delamarche A. Comparison of total antioxidant capacity of salivary, capillary and venous samplings: interest of the salivary total antioxidant capacity on triathletes during training season (2008). J Sports Med Phys Fitness. 48(4):522-9.
  23. Machefer G, Groussard C, Zouhal H, Vincent S, Youssef H, Faure H, Malardé L, Gratas-Delamarche A. Nutritional and plasmatic antioxidant vitamins status of ultra-endurance athletes (2007). J Am Coll Nutr. 26(4):311-6.
  24. Machefer G, Groussard C, Vincent S, Zouhal H, Faure H, Cillard J, Radák Z, Gratas-Delamarche A. Multivitamin-mineral supplementation prevents lipid peroxidation during "the Marathon des Sables" (2007). J Am Coll Nutr. 26(2):111-20,
  25. Gouarné C, Groussard C, Gratas-Delamarche A, Delamarche P, Duclos M. Overnight urinary cortisol and cortisone add new insights into adaptation to training. Med Sci Sports Exerc. (2005) Jul;37(7):1157-67.
  26. Machefer G, Groussard C, Rannou-Bekono F, Zouhal H, Faure H, Vincent S, Cillard J, Gratas-Delamarche A. Extreme running competition decreases blood antioxidant defense capacity. J Am Coll Nutr. (2004) Aug;23(4):358-64.
  27. Groussard C, Machefer G, Rannou F, Faure H, Zouhal H, Sergent O, Chevanne M, Cillard J, Gratas-Delamarche A. Physical fitness and plasma non-enzymatic antioxidant status at rest and after a wingate test (2003). Can J Appl Physiol. Feb;28(1):79-92.
  28. Groussard C, Rannou-Bekono F, Machefer G, Chevanne M, Vincent S, Sergent O, Cillard J, Gratas-Delamarche A. Changes in blood lipid peroxidation markers and antioxidants after a single sprint anaerobic exercise (2003). Eur J Appl Physiol. Mar;89(1):14-20.
  29. Groussard C, Morel I, Chevanne M, Monnier M, Cillard J, Delamarche A. Free radical scavenging and antioxidant effects of lactate ion: an in vitro study (1985). J Appl Physiol 2000 Jul;89(1):169-75.

ARTICLES PUBLISHED IN NATIONAL PEER-REVIEWED JOURNALS

  1. El Hage R, Jacob C, Moussa E, Groussard C, Pineau JC, Benhamou CL, Jaffré C. Influence du statut pondéral sur le contenu minéral osseux et la densité minérale osseuse chez des adolescentes libanaises(2009). Rev Rhum. ; 76 (12): 1337-1342.
  2. Groussard C. Stress oxydatif et exercice anaérobie (2006). Science & Sports.. 21 :62–67.
  3. Rannou F, Groussard C, Gratas-Delamarche A. Evaluation de l'apport calcique chez des sportifs et relation avec les fractures de fatigue (1998). Science et Sports.;13 : 75-80.

SHORT ARTICLES IN NATIONAL PEER-REVIEWED JOURNALS

  1. Groussard C., Youssef H., Lemoine-Morel S., Delamarche P., Pincemail J., Jacob C., Moussa E., Cillard J., Pineau J.C., Gratas-Delamarche A.. 3-month aerobic training attenuates exercise-induced oxidative stress in overweight adolescent girls (2009). International Proceedings. Division. Society for free radical research: Free Radicals, Health and Lifestyle, Roma, Italy,
  2. Youssef H., Groussard C., Moussa E., Jacob C., Pincemail J., Delamarche A..L’insulino-résistance et l’inflammation de repos majorent-elles le stress oxydant post-exercice chez des adolescentes libanaises en surcharge pondérale ? (2007). Science & Sports. ; 22 :  297–299.
  3. Machefer G, Malardé L, Groussard C, Gratas-Delamarche A. Apports et statut en vitamines antioxydantes chez des athlètes d’endurance (2006). Science & Sports. ; 21: 107-109.
  4. Zouhal H, Jacob C, Groussard C, Moussa E, Delamarche P, Gratas-Delamarche A. La réalisation d’un marathon n’affecte pas les performances aérobies mesurées en laboratoire chez des marathoniens de niveau national (2006). Science & Sports ; 21 : 303–305.
  5. Groussard C., Machefer G., Rannou-Bekono F., Gratas-Delamarche A. Evaluation de l'apport en vitamines antioxydantes chez des sportifs (2004).  Science & Sports ; 19: 193-195.
  6. Groussard C., Machefer G., Rannou-Bekono F., Faure H., Cillard J., Gratas-Delamarche A. Effet d’un exercice de sprint sur le statut antioxydant plasmatique (2003).  Science & Sport. 18 (2) : 108-110.
  7. Groussard C., Rouger K., Gratas-Delamarche A., Morel I., Chevanne M., Cillard J., Delamarche P.. Effet du lactate sur la production de radicaux libres: étude in vitro (1999). Science & Sports. ; 14 : 149-152. 

ABSTRACTS PUBLISHED IN PEER-REVIEWED JOURNALS 

  1. Groussard C., F. Rannou-Bekono, G. Machefer, M. Chevanne, M. Monnier, S. Vincent, O. Sergent, J. Cillard and A. Gratas-Delamarche. Short term maximal exercise increase free radical production (2000). The Physiologist, 43 (4): 369,.
  2. Groussard C., G. Machefer, F. Rannou, M. Chevanne, S. Vincent, O. Sergent, J. Cillard and A. Gratas-Delamarche. Un exercice de sprint de 30 secondes génère un stress oxydatif. (2000). Science & sports, 15 (6) : 323,.
  3. Groussard C., G. Machefer, F. Rannou, H. Faure, M. Chevanne, O. Sergent, J. Cillard and A. Gratas-Delamarche. Relationships between antioxidant status, oxidative stress markers and physical level (2001). Pflügers Archiv  European Journal of Physiology, 442 (5): R115.
  4. Machefer G., C. Groussard, F. Rannou, S. Vincent, H. Zouhal, M. Chevanne, J. Cillard, A. Gratas-Delamarche. Oxidatives stress markers and anti-oxidant status during the "Marathon des Sables" competition (2001). Pflügers Archiv  Eur. J. of  Physiology: 442: R118.
  5. Groussard C., G. Machefer, F. Rannou, H. Faure, M. Chevanne, S. Vincent, O. Sergent, J. Cillard, A. Gratas-Delamarche. A short term supramaximal anaerobic exercise induced changes in blood lipid peroxidation markers and enzymatic and non enzymatic antioxidant status (2002). Free Radic. Biol. Med., 33 (S263): 702.
  6. Machefer G, C. Groussard, Rannou F,  Faure H, Chevanne M, Vincent S, Sergent O, Cillard J, Gratas-Delamarche A. Effect of extreme competition oxidative stress on enzymatic and non enzymatic antioxidant status (2002). Free Radic. Biol. Med., 33 (S273): 728.
  7. Groussard C., Gratas-Delamarche A., Morel I., Chevanne M., Monnier M., Cillard J., Delamarche P.. Le lactate exerce t-il un effet direct prooxydant? (1996). Congrès de la Société de Physiologie.  en septembre 1996 à Lille. Le résumé a été publié dans la revue Archives of Physiology and Biochemistry 104, 72-74,

SCIENTIFIC BOOKS

2007-2023 : Translation of the 3rd to 8th edition of the book: Physiology of Sport and Physical Exercise de Wilmore, Costill et Kenney pour les éditions De Boeck Université. En collaboration avec A. et P. Delamarche et H. Zouhal 

 

 


 

[1] Les 2 auteurs ont participé de manière égale au travail et sont dernier auteur.

[2] Les 2 auteurs ont participé de manière égale au travail et sont dernier auteur.

2**-[3] * Je suis dernier auteur à part égale avec A Gratas-Delamarche